Role of cardiovascular magnetic resonance imaging in arrhythmogenic right ventricular dysplasia
نویسندگان
چکیده
Arrhythmogenic right ventricular dysplasia (ARVD) is a genetic cardiomyopathy characterized clinically by ventricular arrhythmias and progressive right ventricular (RV) dysfunction. The histopathologic hallmark is fibro-fatty replacement of RV myocardium. It is inherited in an autosomal pattern with variable penetrance. ARVD is unique in that it most commonly presents in young, otherwise healthy and highly athletic individuals. The cause of ARVD is not well-known but recent evidence suggests strongly that it is a disease of desmosomal dysfunction. The disease involvement is not limited only to the RV as left ventricle (LV) has also been reportedly affected. Diagnosis of ARVD is challenging and is currently based upon a multi-disciplinary work-up of the patient as defined by the Task Force. Currently, implanted cardioverter defibrillators (ICD) are routinely used to prevent sudden death in patients with ARVD. Cardiovascular MR is an important non-invasive diagnostic modality that allows both qualitative and quantitative evaluation of RV. This article reviews the genetics of ARVD, current status and role of CMR in the diagnosis of ARVD and LV involvement in ARVD.
منابع مشابه
MRI of arrhythmogenic right ventricular cardiomyopathy/dysplasia.
Magnetic Resonance Imaging (MRI) is currently considered as the noninvasive modality of choice for evaluation of patients with suspected Arrhythmogenic Right Ventricular Dysplasia (i.e., right ventricular dysplasia). As arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) it is included in the WHO classification of cardiomyopathies. It has the unique ability to provide tissue char...
متن کامل[Clinical value of cardiovascular magnetic resonance imaging in the diagnostic work-up of patients with suspected arrhythmogenic right ventricular dysplasia].
INTRODUCTION AND OBJECTIVES To analyze retrospectively the usefulness of cardiovascular magnetic resonance imaging in the assessment of patients with clinically suspected arrhythmogenic right ventricular dysplasia. MATERIAL AND METHOD We reviewed retrospectively findings from 46 consecutive patients (mean age, 42+/-19 years; 25 male) who were referred for investigation to rule out right ventr...
متن کاملProgress in the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia by Cardiac Magnetic Resonance Imaging Using Feature Tracking.
متن کامل
The Role of Cardiac Magnetic Resonance Imaging in the Evaluation of Arrhythmogenic Right Ventricular Dysplasia
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a cardiac muscle disorder characterized pathologically by fibrofatty replacement of the right ventricular (RV) myocardium [1]. In the early stage of the disease, structural changes may be confined to, the so called "triangle of dysplasia" in the RV. Clinical expression ranges from an asymptomatic phenotype, arrhythmias or eve...
متن کاملThe Correlation between Left and Right Ventricular Ejection Fractions in Patients with Ischemic Heart Disease, Documented by Cardiac Magnetic Resonance Imaging
Introduction: The correlation between right and left ventricular ejection fractions (RVEF and LVEF, respectively) has been studied in only a small number of patients with a marked decrease in RVEF and LVEF. The aim of the present study was to compare LVEF and RVEF in patients with ischemic heart disease. RVEF and LVEF were measured by Cardiovascular Magnetic Resonance (CMR) imaging. Materials a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of Cardiovascular Magnetic Resonance
دوره 10 شماره
صفحات -
تاریخ انتشار 2008